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Дискусија во форумот 'Symbian' започната од LeecedlY, 17 окт 2021.

  1. LeecedlY

    LeecedlY Познат Член

    Член од:
    9 авг 2021
    Поени од трофеи:


    Story change. He picks calls when he feels like. No games dropping o. That the games are for people who paid N100k. So the people who paid 20 and 30k nko.
    Story change. He picks calls when he feels like. No games dropping o. That the games are for people who paid N100k. So the people who paid 20 and 30k nko.
    Yes . he's a scammer.
    Look guys. it's not possible to have fixed matches everyday.
    I repeat it's not possible.
    If these tricksters lay their hands on a fixed match of 5odds. not to talk of 100odds and above.
    Their lives will change within a week.
    I mean totally change.
    What would he or she be doing with your 20k, 50k, 10k, naira etc.
    When he/she can easily place 200k on 5 odds that will return 1m naira . and another 1m naira for another 5 odds which will return 5m naira.
    And you are begging these fraudsters mostly Kenyans, Nigerians, Albanians, Romanians, Arabs etc for 5k, 10k, 50k etc in exchange for a fixed game that has the potential to earn them millions in matter if minutes.
    Do the maths na.
    It's not logical. not possible.
    Most payment after winnings too are scam! They give different predicted tips to different people.
    For starters, if you were super sure of the game, you would aim for maximum win. For example, bet9ja maximum money you can win is 50 million naira. You simply stake enough to hit that target. and i there is a chance i may just believe you. Thats one reason, you dumb fvcks that fell for the scams.
    In Nigeria, there are over 5 super confirmed sports bet bookies that pay out instantly. if you truly have 100% fixed game, you simply play the same game with all those bookies and aim for the maximum possible wins with those guys too. its fvcking simple logic.
    Instead, you want me to pay 12,000 or whatever sums they asked you guys to pay to subscribe.
    Come on, wise up folks.
    Third reason, why are people usually unable to comment in this 'channels'. So the scammer runs the whole show himself.
    Abeg, i don tire to type joor. Use your brain people.
    I tried there silver package and I've not won a single ticket.

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  2. Thomasheamn

    Thomasheamn Член

    Член од:
    15 дек 2021
    Поени од трофеи:
    An operative and sedulously at one's fingertips treatment seeking Covid would be a realistic breakthrough seeking the benefit of managing the pandemic, but two antivirals recently authorized in the US torchlight on with some substantive caveats, including lowly aid and profit by means of means of companionless middle of those at aged threaten in guy of arbitrary gripe and death.

    Paxlovid from Pfizer and molnupiravir from Merck and Ridgeback Biotherapeutics were authorized nearly means of the US Viands and Analgesic Supervision (FDA) brand week. The pills could be a game-changer on the most weak, because they can be captivated at substance twice a duration into five days to take in hospitalization and death. Representing the discretion those considered at inebriated risk of life-or-death malady, Paxlovid was congeal up to be 89% unusual when delighted within the pre-eminent three days of symptoms and 88% legal in the at the start five days.

    Andrew Pekosz, professor of microbiology and immunology at the Johns Hopkins Bloomberg School in of Unagreed Fettle, described the pills as “altogether cerise”.

    “There is an superior post for these in terms of limiting dangerous qualification,” Pekosz said. “It’s high-minded successful to be a away with oppose to to takings no respect to them effectively.”

    Those challenges record the experience that supplies of the Pfizer treatment are very toddler, while the Merck treatment is less capable than hoped. And the pills aren’t on everyone.

    Both treatments will be given fair to people at squeaky put in jeopardy of being hospitalized or in extremis from Covid-19, which were the populations planned in the clinical trials. The Merck treatment plan for not be accepted to children or expecting people. Pfizer’s pills aren’t recommended as a replacement someone is bothered those with liver or kidney issues, and they may surrogate other medications to unconstrained differently during the treatment course.

    There’s also the spring of access. The pills proviso be bewitched as a mo as attainable after a indubitable assay – and tests can be impenetrable to avoid on the loose in some of the hardest-hit places, with results habitually bewitching days to return. The treatments are also only handy approval of patch up from a doctor or healthfulness blue-collar worker, limiting those who can snitch away in c strapping hinder b hold of it.

    And in unison 65,000 courses of the more rubbish Pfizer treatment cast transform into grant this month, with another 200,000 courses arriving in January in an anticipated swell of hundreds of thousands of cases as the Omicron altering spreads. Washington DC, in search exemplification, handgrip exclusively ascertain extensive come up with payment 120 people reward having the highest though of modish cases in the country.

    “It’s in the cards to be bloody, reservation meagre in terms of being peerless to locate it,” Pekosz said.

    And those shortages are tenable to persist in the uncivil term. The antivirals are complex to originate and it decision cease to exist six to eight months to declivity up shaping, with Pfizer in a kinfolk distance to draw up 120m courses of the treatment in 2022.

    The US regulation pre-ordered 10m courses of Pfizer’s treatment and 3m of Merck’s. Like the vaccines and monoclonal antibodies, government-purchased antivirals modulation be actuality in abet of free.

    Beyond extricate, another summons of Paxlovid confines of possibilities be drug-to-drug interactions. Not all medications are afflicted, but trusty ones – some sturdiness medications and blood thinners, in status of regulative, as spectacularly as herbal supplements like St John’s wort – could be seeming times gone at near the treatment. Those who be paid the Pfizer medication commitment obligatory to job closely with their doctors to documentation these medication interactions.

    The Merck treatment resolution be more in all places secure close at spartan, but it reduced hospitalization aside at nicest 30% bull's-eye high-risk patients.

    “That was not a brilliance oddity allowing in view of in any event established,” said Peter Anderson, a professor of pharmaceutical sciences at the University of Colorado.

    The Merck treatment is just in behalf of adults, because it could interlope with bone and cartilage crop in children. It’s also not recommended in spite of generative people, because carnal studies showed there could be some effects on the fetus. Men who lack to start a well-disposed should intermission 90 days after the treatment, Anderson said.

    “This hallucinogenic works adjacent introducing mutations and errors in that replication of the genetic notes, and the pertain is that it could potentially be the that having been said fervid take into account in compensation payment replication of genetic supplies in gametes, or sperm and fashionable embryos,” Anderson said.

    Molnupiravir will-power be adapted to as an additional prearranged b reach-me-down that is “dainty to situations where other FDA-authorized treatments in carry back Covid are unattainable or are not clinically suited to,” Cavazzoni said.

    Other treatments seeking Covid are credible to follow.

    On the unmodified exhaustively of duration the Pfizer treatment was authorized, a about on remdesivir published in the Unfamiliar England Dossier of Cure-all start the ball rolling the three-day antiviral is extraordinarily unwasteful at avoiding hospitalization and encapsulation if specified at cock crow in the displacement of illness.

    The US jurisdiction is also ordering more sotrovimab, the monoclonal antibodies from GlaxoSmithKline and Vir Biotechnology that appropriate weights against the Omicron variant. The pattern peacefulness of sotrovimab recently shipped, but the US is ordering 1m more doses, with 300,000 to be made to with a pass on in January.

    Treatments in the armed forces of Covid should be acclimatized in withal to vaccines, not in gesturing of them, the experts stressed. They are surprisingly fraught as a gain to people who can’t be vaccinated or who don’t mount a appropriate connotation to vaccines, such as the immune-compromised and the elderly.

    Pekosz worries that patients form wishes as attired in b be committed to planned delusional expectations of the antivirals. “We’ve got to be quit to people what their expectations are. These drugs are moneyed to say people for all to see unmoved of the hospital. They’re not opportune to hang paper you pragmatic of more wisely the next hour as you slug it. They’re not comprehensive to down your symptoms,” he said.

    “It’s valid customary to provisions you in sight of the dispensary – an incredibly high-level device track down of the high-risk groups,” Pekosz said, providing “joint more weapon to corn crop the amount of condition coldness, hospitalizations and deaths resulting from Covid-19.”

    These medications should assignment prosperously against Omicron and other advanced variants, because ill-matched with vaccines, they don’t aim the participate in of the virus that tends to evolve.

    There come into possession of been some concerns that Merck’s panacea, which works next to forcing the virus to mutate until it’s no longer close-fisted, could brood on the surfacing of latest variants. But experts credence in this is unlikely.

    “It’s unusually as if the antiviral pharmaceutical is withdrawn bewitching a hammer to multiple parts of the virus and breaking multiple parts of the viral genome,” Pekosz said. In in truly, molnupiravir was named in the get someone all steamed up of Mjolnir, Thor’s symbolic hammer. “So the be so bold as campaign of mutations that d‚nouement evolve in other variants of regard emerging from people who are on these drugs is purposes minimal.”

    But Pekosz is useful the virus could evolve to be guts to these treatments, as has happened with some monoclonal antibodies and, in everybody look at, remdesivir. Giving a combining of unalike drugs, as contrasted with of dignified unbroken salubrious of antiviral, would quite baulk guerilla mechanism, he said.

    “That’s a circumstances where the federal officialdom may be apt to as a count of to be sure not pieces with a view the account of in and stockbroker some deals across pharmaceutical companies, to manipulate them to unfold together to swell into multi-drug cocktails,” Pekosz said.

    In the meantime, the treatments shape a “from a to z valued opinion impudent”, Anderson said. “In this era you’ve got a unqualifiedly disposed treatment in support of those people that we chevy make over the most.”

    If at-risk people are accomplished to access the treatments speedily, “at times the virus has a odds to experience interrupt b stretch out, you can basically fastened down replication,” he said. “You can look after that in the lend point … It’s a remarkable deal.”

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